Structural Biology

The program emphasizes the study of proteins, nucleic acids, and viruses using X-ray crystallography, nuclear magnetic resonance, cryo-electron microscopy, and computational methods to determine how structure informs on the function and mechanism of these biological macromolecules.  Ongoing projects include virus assembly, type III secretion systems of gram negative bacteria, siderophore biosynthesis for iron scavenging by pathogenic bacteria, and ion channels and molecular pores.