Pathogenetic significance of pathological system − Rakyat Biologi

Pathological system underlie a variety of neurological disorders related to various fields of activity of the nervous system, so their education is virtually universal value of pathogenetic factors.

Activities pathological system is clinically expressed as a neuropathological syndrome or symptoms. Each has its syndrome pathological system. Simple, linear pathological system are manifested as symptoms or syndromes monomorphic. An example of a relatively simple system is abnormal pathological system carding pathological reflex described above. Multi-unit, branched pathological systems are pathogenetic basis of complex polymorphic syndromes. As an example of such pathological systems can cause parkinsonism, emotional and behavioral disorders, and others.

Consistently implemented pathogenic triad "generator - pathological determinant - pathological system" is a mechanism of occurrence of various nervous disorders.

This position is the basis of the playback experimental models of various neuropathological syndromes: central pain of spinal origin (generator in the dorsal horns of the spinal cord); trigeminal neuralgia (generator in the caudal nucleus of the trigeminal nerve); thalamic pain syndrome (generator intralaminar thalamic nucleus); vestibulopathy - rat revolves around the longitudinal axis of the body (the generator in the vestibular nucleus of Deiters); photogenic epilepsy (generator in the visual analyzer system - in the lateral geniculate body); pathologically elongated sleep (generator somnogennoy system); psychoaffective complex pathological condition (emotiogenic generator system); abnormal food-getting behavior such as violent behavior (generator in the lateral hypothalamus); parkinsonian syndrome (generator in the caudate nuclei).

One important pathological mechanisms functioning in the system is that it inhibits the physiological systems including antisystems and compensatory processes. This mechanism contributes to the development of the pathological process, especially with the continued action of the etiological factor.