Loss of function of the nervous system

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Loss of one or another function of the nervous system may be due to either the destruction or inhibition of activity of institutions engaged in this function. An example of a loss function due to damage (destruction) of the structure can be flaccid paralysis of the muscles at the death of its innervating motor neurons of the spinal cord affected by poliomyelitis virus, either by suspension or degeneration of the motor nerve. If the damage of structures related to the sensory systems, the sensitivity of the corresponding drop types (pain, visual, etc.).

The degree of loss of function is determined not only by the number of affected nerve cells. Around the lesion in the brain tissue occurs reversibly damaged area and inhibited neurons. Inhibition plays the role of protective mechanisms ( "protective inhibition" according to Pavlov), protecting neurons reversibly damaged, the functional load, which can contribute to their death. Due to switching off of the function of neurons increases the functional level of the defect; This situation occurs when poliomyelitis, traumas of the central nervous system and others. Recovery in a given volume of function is not associated with the regeneration of neurons in therapeutic effects (neurons do not regenerate), and with the improvement of the condition and the normalization of the damaged neurons and reversibly with the removal of protective inhibition.

Loss of function in the event of structural defects is not immediately. It occurs when the damage has reached such a size that has become insufficient compensation mechanisms and overlapping of impaired function. In other words, at this stage of the disease process has made significant development, and does not begin, as is commonly thought. In such cases, the doctor has to deal with quite a neglected disease. That is why the therapy is not always effective even for this, and such an early stage is important for diagnosis of pathological changes in the preclinical stage of the process.

Loss of function due to the inhibition of activity of the central nervous system structures can also occur when the inhibitory effect of strengthening. So if hyperactivity medulla, which normally have a braking effect on the spinal cord reflexes, the spinal reflexes associated with the function falls. Known reflex sensitivity loss, hysterical paralysis, suggestive (hypnotic) movement disorders and sensitivity, and other phenomena of the inhibitory function of suppression.